Tirzepatide for weight loss in stimulant use disorder
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests whether a weekly injection called tirzepatide (a diabetes and weight-loss medication) can help people with obesity and stimulant use disorder reduce stimulant use and lose weight. It aims to see if treating both conditions together improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with moderate to severe methamphetamine, cocaine, or prescription stimulant use disorder.
- You have used stimulants on at least 18 days in the past 30 days.
- Your body mass index (BMI) is 30 or higher, or 27 or higher with a weight-related condition like high blood pressure, diabetes, or sleep apnea.
- You are not currently using any GLP-1 medication, other weight-loss drugs, or insulin.
- You do not have severe kidney disease, uncontrolled diabetes, or a personal or family history of medullary thyroid cancer.
- You can undergo an MRI (no pacemaker or metal in body, and not claustrophobic).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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