Comparing sedative effects on brain waves during gallbladder surgery
Treatments studied
This study is looking at how three different sedative medicines (midazolam, dexmedetomidine, and esketamine) affect brain activity during gallbladder surgery. It aims to find the safest and most precise way to keep you asleep and comfortable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are generally healthy or have only mild health problems (ASA I or II).
- Your body weight is in a healthy range (BMI between 18 and 28).
- You are having a planned laparoscopic gallbladder removal that will last at least 45 minutes.
- You will receive propofol and remifentanil anesthesia with a brain activity monitor (BIS) during surgery.
- You do not have a history of psychiatric or neurological conditions and have not taken certain sedative or antidepressant drugs in the past month.
- You have no known allergies to the anesthetic drugs being tested, and no conditions that would interfere with the brain monitor.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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