Clin2
NCT07701941Possibly a fitRecruiting

Combination treatment for advanced breast cancer

Hormone Receptor PositiveHER2-low or HER2-ultralowUnresectable or Metastatic Breast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This trial tests two targeted drugs together for people with advanced breast cancer that is hormone receptor positive and has low levels of a protein called HER2. The goal is to see if this combination helps shrink tumors or slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
220 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your breast cancer is hormone receptor positive and has low or very low levels of HER2.
  • Your cancer is advanced (can't be removed by surgery or has spread to other parts of the body).
  • You have tried at least one hormone therapy and your cancer progressed while on it.
  • You have taken a CDK4/6 inhibitor (like palbociclib, ribociclib, or abemaciclib).
  • You have not had chemotherapy for advanced breast cancer (chemo before surgery is okay).
  • You are generally in good health (able to carry out daily activities).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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