Can spinal cord stimulation repair small nerve fibers?
Part of Brain & nervous system, Pain clinical trials.
This study tests whether a special type of spinal cord stimulation (which uses mild electrical pulses to block pain) can help repair damaged small nerve fibers in people with small fiber neuropathy. If you have chronic nerve pain and meet the criteria, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years or older.
- You have been diagnosed with small fiber neuropathy based on a skin biopsy that showed a lower-than-normal number of small nerve fibers.
- You have had chronic nerve pain rated as at least 6 out of 10 on a pain scale.
- Your doctor believes you may benefit from a type of spinal cord stimulation therapy that uses a special electrical waveform (ECAP-controlled SCS).
- You are willing to have two skin biopsies (one now and one after 12 months) and complete sensation tests.
- You do not have uncontrolled diabetes (HbA1c over 8.5%), lupus, alcohol abuse, or other reasons that could damage your nerves, and you are not pregnant or planning pregnancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
This trial tests if spinal cord stimulation (a device that sends mild electrical pulses to your spinal cord) can help relieve long-lasting nerve pain in your arm or leg that hasn't gotten better with other treatments. It's for people who have had this pain for at least 6 months and are willing to try a new approach.
This trial tests whether spinal cord stimulation (a device that sends mild electrical pulses to your spine) can help people with severe nerve pain in their neck, back, or limbs who haven't found relief from other treatments. You must already be scheduled to get a specific type of spinal cord stimulator for this study.
This study looks at how spinal cord stimulation (a device that sends mild signals to the spinal cord) affects nerve pain after lumbar surgery. It also aims to help predict who is most likely to improve and why, comparing patients with and without certain sensory symptoms.
This trial tests if a special type of spinal cord stimulation (high-frequency SCS) can better relieve painful nerve damage caused by diabetes. If you have long-term burning, stabbing, or electric-shock-like pain in both legs, this treatment may help reduce that pain.
This trial tests a new type of spinal cord stimulation for people with long-term nerve pain that hasn't improved with other treatments. The goal is to see if this special stimulation pattern can reduce pain better than standard care.
Hear when a new Small Fiber Neuropathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.