Clinical trials
Diabetic Retinopathy clinical trials
Below are recruiting diabetic retinopathy clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07747428Recruiting
Eye imaging study for diabetic retinopathy
This study uses a special eye imaging test called OCT angiography to look at tiny blood vessels in the back of the eye. It aims to understand changes caused by diabetic retinopathy, which could help improve how we monitor and treat this condition.
SohagAges 18–80 - NCT05296447Enrolling by invitationPhase 2
Long-term safety study for diabetic retinopathy gene therapy
This study follows people who already received an injection of RGX-314 (an experimental gene therapy) in a previous clinical trial for diabetic retinopathy, with or without swelling in the macula. It checks the long-term safety and how the treatment works over time.
Phoenix, ArizonaAges Any age - NCT05079399Recruiting
Diabetic eye screening study using eye scans
This study looks for specific eye findings (“biomarkers”) in people with type 2 diabetes using eye imaging. It may help researchers better understand diabetic retinopathy and how to detect it earlier or more accurately.
Carmel, IndianaAges 18 years+ - NCT03403699Recruiting
Stem cell treatment for damaged eye blood vessels in diabetes
This study tests human iPSC–derived (lab-grown) cells aimed at repairing fragile, damaged blood vessels in diabetic retinopathy. It also involves eye exams and a small skin biopsy to support the research.
Birmingham, AlabamaAges 21–98 - NCT04547439RecruitingPhase 2
Melatonin for diabetic eye disease and better sleep
This Phase 2 study tests whether melatonin can improve sleep and possibly outcomes related to diabetic retinopathy (damage to the retina from diabetes). It also checks whether it affects related symptoms while keeping people safe.
Chicago, IllinoisAges 40–65 - NCT06549023Recruiting
One session vs multiple sessions of laser for diabetic eye disease
This study compares having laser treatment for diabetic eye disease in one session versus spreading it over multiple sessions. The goal is to find out if one approach is better for your eyes and easier for you.
MölndalAges 18 years+ - NCT06582472Recruiting
Early eye changes and diabetes trial
This study looks at early damage to the retina (the back of the eye) in people with type 2 diabetes, even before vision problems start. It aims to find new ways to detect and treat diabetic eye disease early.
Milan, Italy/milanAges 40–80 - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80 - NCT06782997Recruiting
Using a quick eye test to check for diabetes eye damage
This trial tests if a special eye exam (electroretinogram) done by a nurse can find early signs of diabetic retinopathy in people with diabetes who have no known eye problems yet. It aims to make screening easier and more accessible.
ReimsAges 18 years+ - NCT06821399Recruiting
Better eye care for type 2 diabetes
This study is testing a better way to diagnose and manage eye problems (diabetic retinopathy) in people with type 2 diabetes. It aims to improve how doctors find and treat these issues to help protect your vision.
LanzhouAges 20–79 - NCT06892353Recruiting
AI eye screening for diabetic retinopathy
This trial tests a new AI-powered, do-it-yourself screening system for diabetic retinopathy. It may help find early signs of eye disease in people who haven't had an eye exam in the past year.
Hong KongAges 18 years+ - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT06955611Recruiting
Is home monitoring safe for early diabetic eye problems?
This trial tests whether monitoring certain diabetic eye changes in the community is as safe as hospital checks. It's for people with early signs of diabetic eye disease that haven't yet reached a more advanced stage.
HaverfordwestAges 18 years+ - NCT07151001Recruiting
AI test for early diabetic eye disease (retinopathy)
This trial uses an AI system to test if it can find early signs of diabetic eye disease (diabetic retinopathy) in people with diabetes. If you have diabetes but no known eye problems, the AI might help catch issues early.
Richmond Hill, New YorkAges 22 years+ - NCT06701721RecruitingPhase 1
Study of THN391 eye injection for diabetic macular edema
This trial tests an experimental eye injection called THN391 for people with diabetic macular edema, a condition that causes vision loss due to swelling in the back of the eye. The study aims to see if the treatment is safe and may help improve vision.
Parramatta, New South WalesAges 18–80 - NCT07351786Recruiting
Newer diabetes drugs and eye protection study
This trial is looking at whether newer diabetes drugs (like SGLT2 inhibitors and DPP-4 inhibitors) can help protect the eyes of people with long-standing type 2 diabetes. The study focuses on preventing or slowing diabetic retinopathy, a common eye complication.
AlexandriaAges 25 years+ - NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT07458516Recruiting
Observing eye disease progression in type 2 diabetes
This study closely follows people with type 2 diabetes who have early signs of diabetic retinopathy (damage to the retina from diabetes) to see how the condition changes over time. It does not test a new treatment but monitors the eye's health closely. It may be a good fit if you have diabetic retinopathy that does not need immediate treatment.
CoimbraAges 35–80 - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Glendale, CaliforniaAges 18 years+ - NCT07634991RecruitingPhase 4
N-acetyl Cysteine for Diabetic Eye Disease
This study tests whether a supplement called N-acetyl cysteine can help slow or improve mild to moderate diabetic eye disease (diabetic retinopathy). The goal is to see if it's safe and effective for people with type 2 diabetes.
CairoAges 18–70 - NCT06191094Enrolling by invitationPhase 4
Vabysmo before eye surgery for bleeding in diabetes
This trial tests if an injection of Vabysmo (faricimab) given before surgery can help people with eye bleeding from diabetic retinopathy. It aims to reduce blood in the eye and improve surgery outcomes.
Aurora, ColoradoAges 18 years+ - NCT05132660Enrolling by invitationEarly Phase 1
Early eye treatment study for diabetic retinopathy
This early-phase study tests a treatment aimed at preventing or slowing early diabetic eye disease in people with mild, early changes. You may be considered if your diabetes is moderately controlled and your eye tests show early warning signs.
Decatur, GeorgiaAges 30–80 - NCT05074342Enrolling by invitation
Project Open study to improve eye screening for diabetes
This study uses health records to see how to increase eye exam screening for people with diabetes who may be at risk of diabetic retinopathy. It aims to help more people get timely eye checks to prevent vision problems.
Toronto, OntarioaAges 18 years+ - NCT07592273RecruitingPhase 2/Phase 3
Gene therapy for diabetic eye disease without macular swelling
This trial tests a gene therapy injection into the eye to treat diabetic retinopathy (eye damage from diabetes) before it progresses. The goal is to slow or prevent vision loss and potentially delay the need for laser treatment or other injections.
Phoenix, ArizonaAges 18 years+
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Diabetic Retinopathy trials by city
Studies with a site in or near these metro areas.
Diabetic Retinopathy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for diabetic retinopathy?
- Yes. Clin2 currently lists 86 recruiting diabetic retinopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetic retinopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetic retinopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.