Desmopressin during complex sellar tumor surgery
Treatments studied
Part of Cancer clinical trials.
This trial tests whether giving desmopressin (a drug that helps the body hold onto water) during surgery can prevent fluid and sodium balance problems in people having complex pituitary or sellar region tumor surgery. It’s designed for those at higher risk of these issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You have a sellar region tumor (like craniopharyngioma or pituitary adenoma) that needs surgery.
- You have at least two of these: diabetes insipidus, a large tumor, a tumor close to the pituitary stalk, or surgery lasting over 4 hours.
- You can stop certain medications (like water pills or antipsychotics) before surgery.
- You don't have serious kidney, heart, or hormone problems, low sodium, or allergies to the trial drug.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving DDAVP before a PET scan can help doctors better locate the pituitary problem in people with Cushing disease. It may help confirm where the ACTH-producing tumor is so surgery can be planned more accurately.
This study tests whether a medicine called desmopressin (DDAVP) can reduce bleeding during heart surgery. It uses a special blood test (TEG6) to decide who gets the medicine.
This study tests whether a protein supplement combined with drinking less fluid can help keep sodium levels stable after pituitary surgery. It is designed for patients who are at risk of sodium imbalances after their operation.
This trial tests a medication called DDAVP to prevent the sodium level from rising too quickly when treating severe low sodium in ICU patients. It is for those with dangerously low sodium and neurological symptoms, but without certain other medical conditions.
This trial tests if a drug called desmopressin can reduce the need for blood transfusions during heart surgery. It is for people at high risk of bleeding, for example because they take blood thinners, have a clotting problem, or need a repeat heart surgery.
This study tests a new type of absorbable (dissolvable) support plate used during minimally invasive surgery to remove tumors in the pituitary gland area. The plate helps support the surgical site as it heals. Researchers want to see if this new plate works safely and effectively compared to standard approaches.
Hear when a new Craniopharyngiomas trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.