Adding birelentinib to standard chemo for newly diagnosed aggressive lymphoma
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests whether adding a new targeted drug called birelentinib to the standard chemotherapy combination (R-CHOP) helps people with newly diagnosed aggressive lymphoma. It aims to improve the chances of remission and reduce the risk of the lymphoma coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been newly diagnosed with a type of aggressive lymphoma called DLBCL (diffuse large B-cell lymphoma), and you have not yet started treatment.
- Your lymphoma is in a more advanced stage (Ann Arbor stage II, III, or IV), and you have a certain risk score (IPI ≥3, or IPI 1-2 with high LDH or a large tumor).
- Your heart, liver, kidney, and bone marrow function are adequate.
- You must be willing to use effective contraception if you or your partner can become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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