Clin2
NCT07715097Likely a fitNot yet recruiting

Survivin vaccine with standard therapy for newly diagnosed glioblastoma

Glioblastoma

Part of Cancer clinical trials.

This trial tests a personalized vaccine made from your own immune cells that targets a protein (survivin) found on your tumor. It is given alongside the standard radiation and chemotherapy to see if it helps fight the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old.
  • You have been newly diagnosed with glioblastoma (a type of brain tumor) and have had surgery to remove as much of it as possible.
  • The tumor is positive for a protein called survivin (a lab test is done to check this).
  • You are generally able to perform your daily activities (a score of 70 or higher on a standard scale).
  • You agree to receive only the standard radiation and temozolomide chemotherapy during the trial, not other brain tumor treatments.
  • You have not had other cancers recently (except cured skin or cervical cancers, etc.) and no serious infections or organ transplant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06524063Not yet recruiting· Phase 1
Immunotherapy targeting survivin for newly diagnosed glioblastoma

This trial tests an experimental immunotherapy made from your own immune cells, designed to train them to attack a protein (survivin) found in glioblastoma. It is a phase 1 study, meaning it is one of the first times this treatment is being tested in people, and it is given alongside standard radiation and chemotherapy.

NCT07678138Not yet recruiting
Personalized dendritic cell vaccine for recurrent glioblastoma

This trial tests an experimental 'vaccine' made from your own immune cells (dendritic cells). The vaccine is designed to train your immune system to attack the brain tumor. It is for people whose glioblastoma has returned or progressed after standard treatment.

NCT07422896Not yet recruiting· Phase 1
B-cell vaccine with standard treatment for glioblastoma

This trial is testing a new vaccine (Bvax) added to the usual chemotherapy and radiation for glioblastoma. It aims to train your immune system to fight the tumor and possibly improve outcomes.

Chicago, Illinois
NCT06749925Not yet recruiting· Phase 3
Personalized immune cell vaccine for glioblastoma

This trial tests a vaccine made from your own immune cells to fight glioblastoma, a type of brain cancer. It may help your body attack the cancer more effectively after standard treatments.

NCT07365280Not yet recruiting· Phase 2
Personalized vaccine with chemotherapy for newly diagnosed glioblastoma

This trial tests a personalized vaccine (made from your own cells) combined with a common chemotherapy drug, temozolomide, for people with newly diagnosed glioblastoma. The goal is to train your immune system to fight the tumor and hopefully slow its growth.

NCT07093814Recruiting· Phase 1/Phase 2
Testing VRT106 injection for recurrent glioblastoma

This trial tests a new injection called VRT106 for people whose glioblastoma (a brain tumor) has come back or is growing. It uses a virus that may help the immune system attack the tumor. This study is for those who have not had a similar virus or gene therapy before.

Hefei, Anhui

Hear when a new Glioblastoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.