Clin2
NCT07718074Possibly a fitNot yet recruiting

Probiotic treatment for severe gum disease

Periodontal Disease

Treatments studied

Part of Mouth & dental clinical trials.

This study tests whether taking a probiotic (a beneficial bacteria) can help treat severe gum disease. For 6 months, you would take either a probiotic or a placebo, and the researchers would check your gum health and measure bacteria and inflammation in your mouth.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
45 years to 65 years
Study type
Interventional

Who can take part

  • You are between 45 and 65 years old
  • You have been diagnosed with severe (Stage III) gum disease
  • You have not taken probiotics, prebiotics, or fiber supplements in the last 6 months
  • You have not taken antibiotics in the last 6 months
  • You have at least 20 natural teeth and do not wear removable dentures
  • You are not pregnant or breastfeeding, and you do not have poorly controlled diabetes or an autoimmune disease

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07672379Not yet recruiting
Probiotic supplement with gum treatment for smokers

This trial tests whether adding a special probiotic supplement (synbiotic) to standard gum disease treatment helps smokers with advanced periodontitis. It may help reduce gum inflammation and improve treatment results.

Istanbul, Istanbul
NCT07725913Recruiting
Gel for gum treatment after deep cleaning

This trial tests if a special gel placed in the gums after deep cleaning helps treat periodontitis (advanced gum disease). You may qualify if you have gum pockets of 5mm or deeper that bleed when probed.

Bologna, BO
NCT07803484Not yet recruiting· Phase 3
Toothpaste study for gum disease after cleaning

This study tests a new toothpaste to see if it helps treat gum disease (periodontitis) after a standard dental cleaning. It may help improve gum health and reduce inflammation.

Porto Alegre, Rio Grande do Sul
NCT07254117Recruiting
Study on gum tissue healing for severe gum disease

This trial tests whether special granulation tissue can help regenerate bone and gum support in people with severe gum disease who still have deep bone pockets after initial treatment. It may offer a better way to heal these defects.

Riga
NCT07443410Recruiting
Probiotics for gum disease treatment

This trial tests whether taking pre- and probiotics alongside non-surgical gum treatment improves healing and reduces harmful bacteria. It may help people with advanced gum disease (stage III or IV periodontitis).

Heidelberg, Baden-Wurttemberg
NCT07531875Recruiting
Probiotics to Help Treat Advanced Gum Disease

This trial tests whether taking probiotics (beneficial bacteria) alongside standard gum disease treatment can help reduce deep pockets in your gums and improve healing. You'd be asked to take probiotics as an add-on to the care you're already receiving.

Kuala Lumpur, Kuala Lumpur

Hear when a new Periodontal Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.