Clin2
NCT07718737Possibly a fitNot yet recruiting

AMT-116 for advanced non-squamous lung cancer after prior treatments

NSCLC (Advanced Non-small Cell Lung Cancer)

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This study tests a new drug called AMT-116 for advanced lung cancer that has not responded to standard treatments. It compares AMT-116 to the doctor's choice of chemotherapy. If you qualify, you'll get either the new drug or a standard treatment, and the goal is to see which works better.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
512 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old.
  • You must have non-small cell lung cancer (NSCLC) that is advanced or has spread, and it must be a type called 'non-squamous'.
  • Your tumor must not have a specific gene change called EGFR mutation.
  • You need to have had at least one prior treatment for your lung cancer, including platinum-based chemotherapy and/or immunotherapy, and your cancer must have gotten worse after that.
  • You should be able to do daily activities (ECOG score 0 or 1) and live at least 12 weeks.
  • Your major organs (blood, kidneys, liver) must work well enough, based on blood tests.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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