Study of roxadustat for anemia in low-risk MDS
Treatments studied
Part of Blood & lymphatic clinical trials.
This trial tests an investigational drug called roxadustat to see if it can help people with a certain type of low-risk MDS who need frequent red blood cell transfusions. It's for patients who haven't responded to other anemia treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of MDS from a bone marrow sample taken within the last 3 months.
- Your MDS should be at a low or intermediate risk level, not high risk.
- You need to have needed at least 4 units of red blood cell transfusions in two 8-week stretches.
- You must have already tried or not be able to take standard anemia drugs called ESAs.
- You should be able to do daily activities with little to no help (able to care for yourself and do light work).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an investigational drug called elritercept for adults with a specific type of low-risk MDS (myelodysplastic syndromes) who have anemia (low red blood cells) and need regular blood transfusions. The goal is to see if elritercept can reduce or eliminate the need for transfusions.
This trial tests an investigational drug called TAK-226 for Japanese patients with a type of bone marrow disorder called lower-risk myelodysplastic syndromes (MDS) who have anemia. It aims to see if the drug can help reduce the need for red blood cell transfusions or improve symptoms like fatigue.
This trial tests an experimental drug, HS-20106, to see if it can improve low red blood cell counts (anemia) for people with a certain type of bone marrow disorder called myelodysplastic syndromes (MDS), which is not high risk. It might be an option if you have not received certain prior treatments.
This Phase 1/2 study tests luspatercept combined with another approach in people with low-risk myelodysplastic syndrome (MDS) who are not responding to or cannot use ESA (a common anemia treatment). It may help improve anemia (low hemoglobin), reduce transfusions, and control the disease if you fit the specific criteria.
This trial tests whether a structured lifestyle program can help people with low-risk myelodysplastic syndromes (MDS) manage their health better. It mainly targets adults who are not getting frequent blood transfusions and have low hemoglobin levels.
This study tests a new drug, momelotinib, for people with a low-risk form of myelodysplastic syndrome (MDS) who need red blood cell transfusions and have already tried one other treatment (like ESAs or luspatercept). The goal is to see if momelotinib can help reduce transfusion needs.
Hear when a new Myelodysplastic Syndromes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.