Clin2
NCT04419649Possibly a fitRecruiting

Elritercept for anemia in lower-risk myelodysplastic syndromes

Myelodysplastic SyndromesCytopenia

Treatments studied

Part of Blood & lymphatic clinical trials.

This trial tests elritercept, a medicine meant to improve anemia (low blood count) in adults with certain lower-risk bone marrow disorders called MDS. If you qualify, the study may help reduce the need for blood transfusions or improve anemia symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
160 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You’re age 18 or older and can give signed informed consent
  • You have MDS that is classified as very low, low, or intermediate risk (or CMML for one part)
  • Your bone marrow blast count is less than 5%
  • Your anemia is significant based on hemoglobin level and/or recent red blood cell transfusions
  • Your white blood cell count is below 13,000 (for key parts of the study)
  • You can follow the study schedule and visit plan

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06499285Recruiting· Phase 3
Study of a new drug to treat anemia in adults with low to intermediate risk MDS who need transfusions

This study tests a new drug called elritercept for people with myelodysplastic syndromes (MDS) who have low blood counts and need regular blood transfusions. The drug aims to boost red blood cell production and reduce or eliminate the need for transfusions, which can improve energy and quality of life.

Duarte, California
NCT05181735Recruiting· Phase 1/Phase 2
Testing luspatercept for low-risk MDS with low hemoglobin

This Phase 1/2 study tests luspatercept combined with another approach in people with low-risk myelodysplastic syndrome (MDS) who are not responding to or cannot use ESA (a common anemia treatment). It may help improve anemia (low hemoglobin), reduce transfusions, and control the disease if you fit the specific criteria.

Amiens
NCT07319845Recruiting· Phase 2
Study of a new drug for anemia in lower-risk myelodysplastic syndromes

This trial tests an investigational drug, TAK-226, for people with lower-risk myelodysplastic syndromes (MDS) who have anemia. The study aims to see if the drug can help improve blood counts and reduce the need for red blood cell transfusions.

Tokyo, Bunkyo-ku
NCT05320198Recruiting· Phase 1/Phase 2
Testing DISC-0974 for anemia in myelofibrosis or MDS

This trial tests an investigational drug called DISC-0974 for people with myelofibrosis or certain types of MDS who have low red blood cell counts (anemia). The goal is to see if this treatment can help improve anemia and reduce the need for blood transfusions.

Gilbert, Arizona
NCT06847867Recruiting· Phase 2
Testing momelotinib for low-risk myelodysplastic syndrome

This study tests a new drug, momelotinib, for people with a low-risk form of myelodysplastic syndrome (MDS) who need red blood cell transfusions and have already tried one other treatment (like ESAs or luspatercept). The goal is to see if momelotinib can help reduce transfusion needs.

Goodyear, Arizona
NCT05384691Recruiting· Phase 2
Luspatercept for anemia in lower-risk MDS not needing transfusions

This Phase 2 trial studies whether luspatercept can improve anemia in people with lower-risk myelodysplastic syndrome (MDS) who do not currently need red-blood-cell transfusions. It’s also looking to see if the benefit is similar whether or not you have ring sideroblasts.

Berlin

Hear when a new Myelodysplastic Syndromes trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.