Lipoic acid for chronic heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether lipoic acid can help people with long-term heart failure. It may improve how well your heart works. The study lasts for a period of time and you will take the study medicine or a placebo (a pill with no active ingredient).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 74 years old.
- You have had heart failure for more than 3 months.
- Your heart's pumping ability (measured by an echocardiogram) is 40% or less.
- You have had a heart attack more than 3 months ago.
- You are in NYHA class II, III, or IV, meaning you have some symptoms like shortness of breath or fatigue.
- You have been on stable heart failure medications for at least 2 weeks, without changes or IV treatments during that time.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study tests a medicine called ALP-1, given as a continuous IV infusion, to see if it can help keep people with advanced heart failure stable and out of the hospital. It may help if you have severe heart failure despite being on all recommended treatments.
This trial tests whether taking vitamin D supplements can improve symptoms and quality of life for people with heart failure. It may help reduce inflammation and support heart function.
This test is looking at whether certain medications (like statins) can help improve blood vessel health in veterans who have heart failure with preserved pumping function. It may help reduce symptoms and keep you out of the hospital.
This trial tests a new medicine called CDR132L to see if it improves heart structure and function in people with heart failure who have a thickened heart muscle and reduced pumping ability. Participants will be randomly assigned to receive either the study drug or a placebo.
This trial compares an LVAD device (a pump placed in the chest) plus medicines versus medicines alone for people with advanced, end-stage heart failure. It aims to see which approach works better to help patients live and stay out of the hospital.
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