Sirolimus for brain health in apoE4 carriers
Treatments studied
Part of Genetic & congenital clinical trials.
This trial tests whether a drug called sirolimus can help protect brain health in women who carry the apoE4 gene, which increases risk for Alzheimer's. You need to be a healthy woman aged 45–65 without any memory problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a woman between the ages of 45 and 65.
- You must carry the apoE4 gene (a genetic risk factor for Alzheimer's).
- You must not have any memory loss diagnosis (like mild cognitive impairment or dementia).
- You must be post-menopausal or using highly effective birth control.
- You must not have certain health problems like poorly controlled diabetes, heart disease, smoking, or heavy drinking.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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