Clin2
NCT07728175Possibly a fitRecruiting

Sirolimus for Alzheimer's risk in women with ApoE4 gene

Genetic Predisposition to DiseaseHealthy VolunteerAPOE-4 Positive

Treatments studied

Part of Genetic & congenital clinical trials.

This study tests whether sirolimus, a medication that may help the body clear damaged cells, can lower Alzheimer's risk in women with the ApoE4 gene variant. It is an early-stage trial that looks at safety and how the drug affects certain blood markers.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
225 people
Ages
45 years to 65 years
Study type
Interventional

Who can take part

  • You are female and between 45 and 65 years old.
  • You carry the ApoE4 gene variant (a common genetic factor that raises Alzheimer's risk).
  • You are either post-menopausal or using reliable birth control.
  • You are generally independent in daily activities and not diagnosed with dementia or memory problems.
  • You do not have major health issues like uncontrolled diabetes, heart problems, or recent stroke.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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