Clinical trials
Genetic Predisposition to Disease clinical trials
Below are recruiting genetic predisposition to disease clinical trials, each written for real people, not researchers. We’re tracking 38 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04760522Recruiting
Genetic testing plan for patients with unclear disease cause
This study helps decide treatment planning based on genetic testing for people whose disease cause is unclear but may be genetic. It’s meant to support a “genomic health” approach, where results guide next steps in care.
TübingenAges Any age - NCT04046796Recruiting
Study genetics in identical twin who differ in symptoms
This study looks at DNA changes to explain why two identical (monozygotic) twins can have different symptoms. It may help clarify the cause of an unclear condition in one twin so the right diagnosis (and future treatment) can be found.
TübingenAges Any age - NCT07181213Enrolling by invitation
Genetic links to high blood pressure
This trial is for people who took part in a large study (SCAPIS) and have both a certain genetic trait and high blood pressure. The goal is to understand how your genes may affect blood pressure.
Linköping, Östergötland CountyAges 50 years+ - NCT06584994Enrolling by invitation
Genetics and cancer risk in families
This study looks at how genes passed down in families might increase the chance of getting cancer. It collects samples from children with cancer and their family members to better understand cancer risks.
CambridgeAges Any age - NCT06057181Recruiting
Helix research network for adults
This study is a research network that collects health information from adults to better understand health and disease. It is open to most adults who are willing to follow the study procedures.
Fort Wayne, IndianaAges 18 years+ - NCT05587439Recruiting
Study of inherited genetic risk in lung and related cancers
This study looks for inherited (family-passed) genetic changes that may raise the risk of lung cancer and related thoracic cancers. It may help people and families understand their genetic risk by collecting health information and sometimes specimens from patients and relatives.
Boston, MassachusettsAges 18 years+ - NCT04427163Recruiting
Study of health differences using blood and data profiles
This study looks at how people’s health and disease risk show up in multiple types of information collected together (like blood-related measures and other data). It may help researchers understand what patterns are linked to health versus future disease.
OlomoucAges 18–68 - NCT03931707Recruiting
Genetic study of newborns in China
This study collects genetic information from very young newborns to better understand early-life health. Your child’s information may help researchers learn about genetics and future research.
Shanghai, Shanghai MunicipalityAges Up to 4 weeks - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT05656261Recruiting
Genetic testing study for African Americans
This study looks at genetic markers (genes) related to kidney risk in Black/African American adults. It may help researchers better understand who is at higher risk and how genetics could guide future care.
St Louis, MissouriAges 18–90 - NCT05597904Recruiting
Study differences in celiac disease and related skin rash
This study looks at why celiac disease (and a related skin condition called dermatitis herpetiformis) can look different from person to person. It may help researchers understand these “phenotypes” (different patterns) so future care can be better targeted.
TampereAges 18 years+ - NCT04731857Recruiting
Genetic testing results study for rare diseases
This study looks at how well different genetic tests (whole exome/genome sequencing and standard genetic tests) work for diagnosing rare genetic diseases and inherited cancer conditions. It may help confirm which testing approach provides the clearest results for families.
TübingenAges Any age - NCT07112287Recruiting
Germline testing for myeloid cancer risk
This trial studies whether certain inherited genes increase the risk of myeloid cancers or bone marrow failure. You will provide a DNA sample via a skin biopsy to look for these genetic changes.
Boston, MassachusettsAges 18 years+ - NCT06993142Recruiting
Slowing Parkinson's Early With Exercise
This trial tests whether a specific exercise program can slow the early stages of Parkinson's disease in people who have a genetic risk (LRRK2 or GBA variants). You will use a smartphone app to guide your exercise from home.
Rochester, New YorkAges 50 years+ - NCT03538639Recruiting
Study blood and tissue samples for vascular disease discovery
This study collects blood (and sometimes tissue samples) from people who may have vascular (blood vessel) problems and from certain pregnant participants. Researchers use the samples to better understand vascular disease and to help guide future research.
Bethesda, MarylandAges 2–100 - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT04903782Recruiting
Family whole-genome testing for children with newly diagnosed cancer
This study offers whole-genome testing (a way to read a person’s DNA) to families after a child is newly diagnosed with cancer. It aims to find inherited changes that may explain why cancer happened and guide future care or monitoring.
Newcastle, New South WalesAges Up to 21 years - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74 - NCT05661305Recruiting
Egyptian healthy adults for heart and MRI study
This trial studies how healthy hearts work in Egyptian adults who do not have known heart problems. It may help researchers understand heart health and risk factors, using an MRI scan.
AswānAges 18 years+ - NCT06020625Recruiting
Genetic testing for advanced cancers
This trial investigates genetic testing (mutational profiling) in people with various advanced cancers. It aims to understand how these tests can guide more personalized treatment decisions.
RomeAges 18 years+ - NCT05661318Recruiting
Study of heart health in Ballana adults
This study is looking at heart health in adults living in Ballana. Your involvement could help researchers understand local heart risks and needs in the community.
AswānAges 18 years+ - NCT05772559Recruiting
Study of AML genes and drug response in young patients
This trial looks at how childhood, teen, and young adult acute myeloid leukemia (AML) changes at the genetic level and how cells respond to multiple drugs. It may help doctors understand which treatments work best and how leukemia interacts with supportive cells in the bone marrow.
AmiensAges Up to 25 years - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT07728175RecruitingPhase 1
Sirolimus for Alzheimer's risk in women with ApoE4 gene
This study tests whether sirolimus, a medication that may help the body clear damaged cells, can lower Alzheimer's risk in women with the ApoE4 gene variant. It is an early-stage trial that looks at safety and how the drug affects certain blood markers.
Columbia, MissouriAges 45–65
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Genetic Predisposition to Disease trials by city
Studies with a site in or near these metro areas.
Genetic Predisposition to Disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for genetic predisposition to disease?
- Yes. Clin2 currently lists 38 recruiting genetic predisposition to disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic predisposition to disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic predisposition to disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.