Stopping GLP-1 drugs before colonoscopy: a trial in Taiwan
Part of Digestive system clinical trials.
This study looks at whether stopping GLP-1 receptor agonists (a type of diabetes or weight-loss medication) before a colonoscopy can help improve the procedure. It compares how well the bowel is cleaned in people who stop these drugs for a certain time versus those who continue them.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You are scheduled for a full colonoscopy for any reason.
- You are generally well enough to have a colonoscopy (ECOG score 0 or 1).
- If you take medications that slow down your bowels, you stop them at least 3 days before the procedure.
- You do not have certain serious medical conditions (like recent heart attack, unstable angina, severe lung disease, or bleeding problems).
- You have not had parts of your stomach, small intestine, or colon removed (except appendix removal).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a special bowel preparation plan works better for people taking GLP-1 or GIP medications (like Ozempic, Mounjaro) before a colonoscopy. It aims to improve the quality of the bowel cleaning so doctors can see the colon more clearly.
This trial is testing whether stopping GLP-1 receptor agonists or tirzepatide one week before an upper endoscopy (a scope that looks at your stomach and esophagus) is safe and effective. It's designed for people who are already taking these medications and have an upcoming procedure.
This study is for people who have lost weight using semaglutide or tirzepatide and are stopping that medication. It tests a stomach procedure (called mucosal ablation) to see if it can help you keep the weight off after stopping the drug.
This study looks at whether stopping a type 2 diabetes medication called GLP-1 receptor agonists for two weeks before an upper endoscopy can reduce the risk of food staying in the stomach during the procedure. If you are scheduled for an upper endoscopy and take this medication, this trial may help make your procedure safer and more comfortable.
This study uses an ultrasound to look at how full your stomach is after taking GLP-1 medications for diabetes or weight loss. It will help doctors understand if current fasting guidelines are safe before surgery or a colonoscopy.
This study looks at whether people taking weekly GLP-1 medications (like Ozempic or Wegovy) should follow standard fasting rules or a 24-hour clear liquid diet before a procedure. The goal is to find the safest way to prepare.
Hear when a new GLP-1 trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.