Should you pause your diabetes medication before a stomach scope?
Part of Digestive system, Hormones & metabolism clinical trials.
This trial is testing whether stopping GLP-1 receptor agonists or tirzepatide one week before an upper endoscopy (a scope that looks at your stomach and esophagus) is safe and effective. It's designed for people who are already taking these medications and have an upcoming procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently taking a GLP-1 receptor agonist or tirzepatide.
- You have been on this medication for at least 4 weeks or are on a high maintenance dose.
- You are between 18 and 70 years old.
- You are scheduled for an upper endoscopy (EGD) for any reason.
- You are able to stop certain medicines that affect stomach movement at least 3 days before the procedure.
- You do not have severe health problems that would make the endoscopy risky (like heart issues or liver cirrhosis).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether stopping GLP-1 receptor agonists (a type of diabetes or weight-loss medication) before a colonoscopy can help improve the procedure. It compares how well the bowel is cleaned in people who stop these drugs for a certain time versus those who continue them.
This study tests whether a special bowel preparation plan works better for people taking GLP-1 or GIP medications (like Ozempic, Mounjaro) before a colonoscopy. It aims to improve the quality of the bowel cleaning so doctors can see the colon more clearly.
This study is for people who have lost weight using semaglutide or tirzepatide and are stopping that medication. It tests a stomach procedure (called mucosal ablation) to see if it can help you keep the weight off after stopping the drug.
This study looks at whether pausing GLP-1 agonist medications (like Ozempic or Trulicity) for two weeks before an upper endoscopy can reduce the chance of food staying in the stomach during the procedure. It may help people who take these diabetes medicines and need a routine endoscopy.
This study checks if stopping semaglutide (a diabetes/weight-loss drug) for one week before a sedated endoscopy helps reduce leftover food in the stomach and improves how well doctors can see the stomach lining. It may help patients who need a clear view during the procedure.
This study looks at whether people taking weekly GLP-1 medications (like Ozempic or Wegovy) should follow standard fasting rules or a 24-hour clear liquid diet before a procedure. The goal is to find the safest way to prepare.
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