GLP-1 medications and colonoscopy prep quality
Part of Digestive system, Hormones & metabolism clinical trials.
This study tests whether a special bowel preparation plan works better for people taking GLP-1 or GIP medications (like Ozempic, Mounjaro) before a colonoscopy. It aims to improve the quality of the bowel cleaning so doctors can see the colon more clearly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have a scheduled outpatient colonoscopy (for screening, surveillance, or diagnosis).
- You take a GLP-1 or GIP agonist (like Ozempic, Wegovy, Mounjaro, etc.) at a stable dose for at least one month.
- You agree to follow the study's bowel preparation plan: a split-dose laxative (4 liters of polyethylene glycol + 15 mg bisacodyl), a low-residue diet for 3 days before, and clear liquids the day before.
- You do not have certain health conditions (like cirrhosis, Parkinson's, dementia, gastroparesis, or a history of poor bowel prep) that could affect prep quality.
- You are not using tricyclic antidepressants or opioids.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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