Immunotherapy plus targeted therapy and chemotherapy for advanced neuroendocrine cancer
Part of Cancer clinical trials.
This trial tests a combination of two immunotherapy drugs (iparomlimab and tuvonralimab), a targeted therapy (lenvatinib), and chemotherapy for people with neuroendocrine carcinoma that has spread or cannot be removed by surgery. The goal is to see if this combination helps shrink tumors and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of neuroendocrine carcinoma that started outside the lungs and has spread or cannot be surgically removed.
- You are 18 years or older.
- You have not had prior systemic treatment for advanced disease, but you may have had adjuvant therapy after surgery if the cancer returned more than 6 months later.
- You are in generally good health (able to do daily activities) and have adequate organ function.
- You have at least one measurable tumor (as seen on scans).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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