Clin2
NCT05058651Possibly a fitRecruiting

Atezolizumab plus chemo for advanced neuroendocrine cancer outside the lung

Advanced Extrapulmonary Neuroendocrine CarcinomaMetastatic Extrapulmonary Neuroendocrine CarcinomaRecurrent Extrapulmonary Neuroendocrine CarcinomaUnresectable Extrapulmonary Neuroendocrine Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests whether adding an immunotherapy drug called atezolizumab to standard chemotherapy helps people with advanced neuroendocrine carcinoma (a rare and aggressive cancer) that started outside the lung. The goal is to see if the combination works better than chemo alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
189 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a type of cancer called poorly differentiated neuroendocrine carcinoma that started outside the lung.
  • Your cancer cannot be removed with surgery or has spread to other parts of the body.
  • You have not had prior treatment for advanced disease, except you may have had one round of chemo with a platinum drug and etoposide.
  • You have not taken immune checkpoint inhibitors (like PD-1 or PD-L1 blockers) for this cancer before.
  • You are generally well enough to carry out daily activities (performance status 0–2).
  • Your kidney, liver, and blood counts meet certain levels as determined by your doctor.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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