Comparing bronchoscopic microwave ablation and surgery for early-stage lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This study looks at two ways to treat early-stage lung cancer: using heat from a tiny probe passed through the airways to kill the tumor (microwave ablation), or surgery to remove the tumor and some surrounding tissue. The goal is to find which approach is more effective and safer for people with this type of lung cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have early-stage non-small cell lung cancer, with a tumor 3 cm or smaller that hasn't spread to lymph nodes or other parts of the body.
- A team of doctors will decide if you're better suited for bronchoscopic ablation (which uses heat to destroy the tumor) or surgery to remove it.
- For the ablation group, the tumor needs to be in the outer part of the lung and smaller than 2.5 cm, and you should have reduced lung function or other reasons to preserve lung tissue.
- For the surgery group, the tumor may be larger (up to 3 cm) or located near the center of the lung, and you must be healthy enough for general anesthesia.
- You cannot have certain heart implants (like a pacemaker) that could be affected by microwave energy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two non-surgical treatments for early-stage lung cancer: microwave ablation (a procedure that uses heat to destroy the tumor) and stereotactic body radiotherapy (a precise type of radiation). The goal is to see if these treatments are equally effective in controlling the cancer while slowing down progression.
This study tests a new, less invasive way to treat lung cancer using microwave energy delivered through a thin tube inserted into the airway. It is for people with small, confirmed lung tumors who are already being considered for surgery, and who cannot or prefer not to have blood thinners.
This trial tests a minimally invasive procedure that uses microwave energy to destroy lung tumors. It is for people who are already candidates for surgery but may want a less invasive option.
This trial compares two types of radiofrequency ablation (a heat-based treatment) for early-stage lung cancer that is located in the outer parts of the lung. One approach uses a needle through the chest wall, the other uses a bronchoscope through the airways. The goal is to see which works better for people who cannot have surgery.
This study tests a new microwave device that uses heat to destroy small lung tumors. It may be an option if your nodule is 20 mm or smaller and cannot be removed with surgery.
This trial tests a minimally invasive procedure using microwave energy to destroy small lung tumors, guided by a thin tube through the airways. It may be an option if you can't have standard surgery or radiation, or choose not to.
Hear when a new Stage IA NSCLC trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.