Combining CPAP and a sleep medication for sleep apnea with insomnia
Treatments studied
Part of Brain & nervous system, Lungs & breathing, Mental health clinical trials.
This study tests combining a CPAP machine with a sleep medication called daridorexant to treat people who have both sleep apnea and insomnia. It aims to see if this combination therapy is safe and effective for people who are just starting treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (18 or older) and have just been diagnosed with both sleep apnea and insomnia, known as COMISA.
- Your sleep apnea is moderate to severe (at least 15 breathing pauses per hour of sleep) and your insomnia is significant (score of 15 or more on a standard insomnia questionnaire).
- You haven't used a CPAP machine or taken daridorexant (a sleep medicine) for more than 5 years.
- You are willing to start using a CPAP machine and take daridorexant as part of this study.
- You are covered by French national health insurance and can give your written consent to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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