Study of MRT-2359 with apalutamide for prostate cancer
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a new oral drug, MRT-2359, combined with apalutamide (a standard hormone therapy) in men with a specific type of prostate cancer that has stopped responding to hormone treatment. The goal is to see if the combination can slow or stop the cancer's growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old.
- You have a type of prostate cancer that no longer responds to hormone therapy (castration-resistant) and has a specific change in the androgen receptor gene.
- You have had at least one prior hormone therapy (like enzalutamide or abiraterone) for your prostate cancer.
- You have not had more than one prior chemotherapy regimen (like docetaxel or cabazitaxel) for your cancer.
- You have not been treated with an AR degrader or similar drug before.
- You are willing to provide a tumor biopsy during screening.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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