Clin2
NCT07750132Possibly a fitNot yet recruiting

Study of a new drug for advanced tumors that test positive for egfr and pd-l1

Advanced Solid Tumors

Part of Cancer clinical trials.

This study tests a new drug called SM2275, given as an injection, for people with advanced solid tumors that have EGFR and PD-L1 markers. The goal is to see if the drug is safe and effective, and it might help if other treatments haven't worked.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
72 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • Your cancer must be advanced or has spread, and it must test positive for EGFR and PD-L1 markers. Common types include head and neck cancer, non-small cell lung cancer, colorectal cancer, or kidney cancer.
  • Standard treatments either didn't work, caused too many side effects, or aren't available for your situation.
  • You need to have at least one measurable tumor (one that can be seen on scans) and be able to provide a tumor sample.
  • You should be in fairly good health overall — able to take care of yourself (ECOG score 0 or 1) and have a life expectancy of at least 3 months.
  • Your heart, liver, kidneys, and blood counts must be within acceptable ranges, and you must not have serious heart or lung conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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