Valve implant for severe leak without calcification
Part of Heart & circulation clinical trials.
This study tests a new valve replacement for people with severe aortic regurgitation (leaky heart valve) who are not good candidates for open surgery. The valve is put in through a small tube in the leg, which may be less risky for high-risk patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your doctors agree that traditional open-heart surgery is too risky because of other health conditions.
- You have severe aortic regurgitation (leaky valve) without significant calcium buildup or narrowing.
- You have symptoms like breathlessness, fatigue, or chest pain (classified as NYHA Class II or higher).
- You are able to have the procedure through a catheter in your leg (not through open surgery).
- You agree to return for all follow-up visits after the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
This trial compares a new catheter-based valve (J-Valve) with open-heart surgery for people with severe aortic regurgitation, a condition where the aortic valve doesn't close tightly. It aims to see which treatment is safer and more effective.
This study tests a less invasive procedure to replace a leaky aortic valve in people who can't have open-heart surgery. The goal is to help your heart pump better and reduce symptoms.
This trial tests whether a 3D computer simulation can help guide a less invasive procedure (TAVR) to replace a leaky aortic valve. It may be an option for people with severe aortic regurgitation who are at least 65 years old.
This trial studies a less invasive heart valve procedure that places a new valve through a catheter, to treat severe leakage of the aortic valve. It may help people who have symptoms or heart enlargement and who are at higher risk for open-heart surgery.
This study is tracking how well the Myval valve works in people with severe aortic stenosis who get it through a minimally invasive procedure called TAVI. It helps doctors learn more about the valve's safety and performance in real-world use.
Hear when a new Aortic Regurgitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.