Clin2
NCT07752264Possibly a fitNot yet recruiting

CAR T-cell therapy for immune-mediated necrotizing myopathy

Refractory Immune-mediated Necrotizing Myopathy

Treatments studied

Part of Bones, joints & muscles, Immune system & allergy clinical trials.

This trial tests a new treatment called Eque-cel, which uses your own immune cells to target and destroy the cells causing muscle damage. It is for people with a specific type of inflammatory muscle disease that has not improved with standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
27 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with immune-mediated necrotizing myopathy (IMNM).
  • Your blood tests show a positive anti-SRP or anti-HMGCR antibody.
  • You have tried standard treatments but your disease is still active or has come back.
  • You agree to use effective birth control during the study and for one year after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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