Mitral Valve Repair Using Polares System for Heart Failure
Part of Heart & circulation clinical trials.
This trial tests a minimally invasive procedure to repair a leaky mitral valve (the valve between the upper and lower chambers of your heart) in people with heart failure who haven't improved with medication alone. The procedure uses a catheter-based system inserted through the groin to replace part of the valve, potentially reducing symptoms and improving heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Moderate-to-severe leaky mitral valve (grade 3+ or higher) confirmed by ultrasound within 60 days
- Heart failure symptoms (NYHA Class II, III, or ambulatory IV) despite maximum tolerated heart medications stable for 30 days
- Age 21 or older
- Deemed high-risk but operable for heart surgery (STS score less than 10%)
- Unsuitable for other catheter-based mitral valve treatments per your heart team
- Able to return for all follow-up visits and willing to participate
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This study looks at how long a new mitral valve treatment/device can stay working in people with moderate-to-severe or severe mitral valve leak. It may help avoid or delay surgery for people considered higher risk for mitral valve repair.
This trial studies a minimally invasive mitral valve repair/replacement approach for people with severe mitral regurgitation (leaky mitral valve) who are not good candidates for standard surgery or catheter options. It may help improve symptoms by treating the leaky valve when other treatments aren’t suitable.
This study is for people with severe mitral valve leakage (mitral regurgitation) who may need a valve replacement. It tests whether the ReValve system is safe and can help improve symptoms and heart function.
This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
This study tests a new device, MRace, for people with severe functional mitral regurgitation, a condition where the heart's mitral valve doesn't close fully, causing blood to leak backward. The trial is for patients who have unusual heart structures that make the standard clip procedure difficult. The goal is to see if MRace can safely and effectively fix the leak and improve symptoms.
Hear when a new Mitral Regurgitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.