Oxidative stress and heart risk in rheumatoid arthritis
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This study looks at how oxidative stress (an imbalance of harmful molecules in the body) relates to cardiovascular risk in people with rheumatoid arthritis. It aims to see if these factors are linked, which could help in better managing heart health for RA patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 69 years old
- You have been diagnosed with rheumatoid arthritis
- You are currently taking a disease-modifying antirheumatic drug (DMARD) or biologic therapy
- If you take corticosteroids (like prednisone), the dose must be 10 mg or less per day and stable for at least one month
- You do not have other autoimmune rheumatic diseases (except Sjögren's associated with RA)
- You do not have other inflammatory joint diseases (like gout, psoriatic arthritis, reactive arthritis, or Lyme disease)
- You have normal kidney function (eGFR ≥ 60)
- You are not pregnant or breastfeeding
- You do not have severe uncontrolled heart, lung, liver, endocrine (including diabetes), or gut disease
- You weigh no more than 150 kg
- You have no history of alcoholism or drug abuse in the past 6 months
- You are willing to provide written informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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