Matching immunotherapy and targeted radiation for advanced cancer
Treatments studied
Part of Cancer, Digestive system, Lungs & breathing, Women’s health & pregnancy clinical trials.
This trial tests combining immunotherapy (a treatment that boosts your immune system to fight cancer) with a targeted type of radiation called SBRT, which precisely delivers high-dose radiation to multiple cancer spots. The main goal is to see if this combination helps control metastatic cancer (cancer that has spread) better than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have one of these cancers: head and neck, non-small cell lung, cervical, esophageal, gastric, or gastroesophageal.
- Your cancer has spread to at least 6 separate spots (metastases) that are treatable with a type of focused radiation called SBRT. These spots can be in the lungs, liver, adrenal glands, bones, or lymph nodes.
- You are eligible to receive immunotherapy, and this is your first immunotherapy-based treatment. You may have had other cancer treatments before.
- If you had chemotherapy or radiation, it must have finished at least 3 weeks before starting the trial (except for certain brain radiation).
- Your overall health is good, with a performance status of 0 or 1, and you are expected to live at least 6 more months.
- Your blood tests show adequate organ and bone marrow function, and you do not have active serious infections or uncontrolled health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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