Predicting ARDS and death after severe chest injury with blood proteins
Part of Injuries & trauma, Lungs & breathing clinical trials.
This study is testing whether certain proteins in the blood (sRAGE, CC16, and Syndecan-1) can help predict if patients with severe chest trauma will develop a serious lung condition called ARDS or have a higher risk of death. By measuring these proteins early, doctors might be able to identify high-risk patients sooner and provide more targeted care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old.
- You must have a severe chest injury (blunt or penetrating) within the last 24 hours.
- You must be admitted to a trauma unit or intensive care unit.
- You must not have certain pre-existing conditions (e.g., chronic lung disease, active cancer, pregnancy).
- You must not have major injuries outside the chest.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
This study looks at a blood marker (EV-TF) to see whether it helps predict pulmonary embolism—blood clots in the lungs—in people with ARDS who are in the ICU. Results may help doctors better identify who is at higher risk.
This study looks at different types of inflammation in patients with Acute Respiratory Distress Syndrome (ARDS), a serious lung condition. It aims to find which treatments work best for each subtype.
This study looks at a new way to predict how serious ARDS (a severe lung injury from pneumonia) is and the chance of death. Doctors will measure something called "elastic power" to see if it helps guide treatment for patients on a breathing machine.
This study looks at whether a simple blood test measuring fibrinogen and albumin levels can help predict if someone with a traumatic brain injury will develop a serious lung condition called acute respiratory distress syndrome (ARDS). It may help doctors identify patients who need extra monitoring and care.
This study is for patients in the ICU with ARDS (a severe lung condition). It looks at biomarkers (special substances in your blood) to help understand different types of ARDS. You do not receive any treatment, but you help researchers learn more about the disease.
Hear when a new Acute Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.