First-line treatment for metastatic non-squamous lung cancer with RAS mutation
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests whether adding a new drug (zoldonrasib) to standard chemotherapy and immunotherapy can help people with a specific type of lung cancer. It is for those with a RAS G12D mutation and no prior treatment for metastatic disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old.
- Have metastatic non-squamous non-small cell lung cancer that has not been treated before.
- Have a specific RAS G12D mutation (a change in the cancer cells).
- Be able to take oral medications.
- Have adequate organ function (kidneys, liver, bone marrow, etc.).
- No untreated brain metastases.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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