Timing of sufentanil to prevent coughing during anesthesia
Treatments studied
Part of Lungs & breathing clinical trials.
This study tests different timing for giving a painkiller called sufentanil before placing a breathing tube during general anesthesia, to reduce coughing during the procedure. If you're having planned surgery under general anesthesia and don't have certain lung or heart conditions, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and are scheduled for elective (non-emergency) surgery that requires general anesthesia with a breathing tube.
- You are in good general health (American Society of Anesthesiologists class I–III).
- Your blood pressure and heart rate are within normal limits when you arrive at the hospital.
- You do not have a history of chronic cough, asthma, COPD, or other active lung disease, and no recent respiratory infection.
- You have not been on regular opioid painkillers recently, and you are not taking medications that could affect your cough reflex.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares a new painkiller (oliceridine) to a standard one (sufentanil) to see which works better at stopping coughing when you first go under anesthesia for surgery. It may help you have a smoother start to your procedure.
This trial compares three drugs (dexmedetomidine, magnesium sulfate, and lidocaine) to see which best prevents coughing when waking up from anesthesia. It is for adults between 21 and 60 who are having surgery and are in good general health.
This study compares two medicines given while the breathing tube is removed after thyroid surgery. It aims to reduce coughing and discomfort, making recovery more comfortable.
This trial tests whether tegileridine causes less coughing than sufentanil when given as part of anesthesia for surgery. It aims to find a better painkiller option for patients having surgery with a breathing tube.
This trial tests whether adding lidocaine or sufentanil to a standard anesthetic drug (etomidate) helps reduce the dose of remifentanil needed to place a breathing tube comfortably. It may help patients undergoing planned surgery with general anesthesia.
This trial tests the pain medicine sufentanil to see how it affects blood pressure and heart rate during brain bypass surgery. It may help doctors better manage anesthesia for people having this type of surgery.
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