Clin2
NCT06979141Possibly a fitRecruiting

Cough prevention after general anesthesia

Cough

Treatments studied

Part of Lungs & breathing clinical trials.

This trial compares three drugs (dexmedetomidine, magnesium sulfate, and lidocaine) to see which best prevents coughing when waking up from anesthesia. It is for adults between 21 and 60 who are having surgery and are in good general health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
300 people
Ages
21 years to 60 years
Study type
Interventional

Who can take part

  • You are between 21 and 60 years old.
  • You are not pregnant or breastfeeding.
  • You have a body mass index (BMI) under 30.
  • You are in good health (classified as ASA I or II) and have a clear airway (Mallampati score I or II).
  • You are having surgery under general anesthesia.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07778953Not yet recruiting
Preventing cough during anesthesia induction

This study tests a way to give a common pain medicine during anesthesia to reduce coughing when a breathing tube is placed. It aims to find the best dose for adults having scheduled surgery with general anesthesia.

Shaoyang, Hunan
NCT07660380Recruiting· Phase 4
Comparing Two Painkillers for Cough During Anesthesia

This study compares a new painkiller (oliceridine) to a standard one (sufentanil) to see which works better at stopping coughing when you first go under anesthesia for surgery. It may help you have a smoother start to your procedure.

Tianmen, Hubei
NCT05821972Recruiting· Phase 4
Breathing-mist medicines for cleft palate surgery pain control

This trial tests whether a breathing mist of two medicines (dexmedetomidine plus ketamine) works better than dexmedetomidine alone during cleft palate repair surgery. It may help improve comfort and safety around anesthesia for eligible patients.

Asyut
NCT07355049Not yet recruiting
Preventing agitation after sinus surgery with sedation or numbing medicine

This study tests two different medications (dexmedetomidine and lidocaine) to see which one better prevents agitation when waking up after sinus surgery. If you're having elective sinus surgery and are in generally good health, you may be able to join.

Al Fayyum
NCT07213037Not yet recruiting· Phase 3
Drugs to control cough after sinus surgery

This study tests whether adding magnesium sulfate or lidocaine to the usual drug helps stop coughing after sinus surgery. It may help you breathe more comfortably after your procedure.

NCT07709390Not yet recruiting· Early Phase 1
Lidocaine gel on breathing tube for surgery

This trial tests whether putting lidocaine gel on the breathing tube before surgery can reduce post-operative sore throat and coughing. It aims to make recovery more comfortable for patients having general anesthesia.

Columbus, Ohio

Hear when a new Cough trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.