Clin2
NCT07779798Possibly a fitNot yet recruiting

CBX-663 for advanced blood cancers, solid tumors, or glioblastoma

Advanced Solid TumorsRecurrent or Progressive GlioblastomaRelapse or Refractory Myeloid Malignancies

Part of Blood & lymphatic, Brain & nervous system, Cancer clinical trials.

This trial tests a new drug called CBX-663 in people with certain blood cancers, solid tumors, or glioblastoma that have returned or not responded to standard treatment. It aims to see if the drug is safe and helps shrink or control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old.
  • You must have a specific type of blood cancer (AML, MDS, or CMML), a solid tumor, or glioblastoma that has not responded to treatment or has come back.
  • You must have a specific genetic marker called HLA-A*02:01.
  • You must be in generally good health (able to do daily activities on your own or with minimal help).
  • Your kidney and liver function must be within a certain range.
  • You must not have active infections or certain heart conditions, and you must not be pregnant or nursing.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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