Nerve procedure versus Botox for chronic migraine
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study compares two treatments for chronic migraine: a nerve stimulation procedure called pulsed radiofrequency and Botox injections. Both are known to help some people with chronic migraine, and the goal is to see which one works better at reducing headache days and improving quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have chronic migraine, meaning headaches on 15 or more days per month for at least 3 months, with migraine features on at least 8 of those days.
- You have tried at least one standard preventive migraine medication (like amitriptyline, propranolol, or topiramate) and it didn't help enough, caused side effects, or you couldn't take it.
- Your current migraine prevention medication (if any) has been at a stable dose for at least 4 weeks before the study starts.
- You are willing to fill out headache diaries and attend follow-up visits.
- You have not had Botox or a nerve radiofrequency procedure for headaches in the last 6 months, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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