Two migraine medicines together for chronic migraine
Part of Brain & nervous system clinical trials.
This trial tests whether using both a CGRP antibody and Botox together works better than the CGRP antibody alone for chronic migraine. It may help if you have not tried these treatments before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 70 years old.
- You have been diagnosed with chronic migraine (15 or more headache days per month for at least 3 months).
- You have not had Botox or any CGRP inhibitor treatment before.
- You are willing to use effective birth control if you could become pregnant.
- You have not had a heart attack, stroke, or certain heart procedures in the last year.
- You can tell the difference between migraine and other headache types.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two treatments—botulinum toxin injections and nerve blocks in the neck—to reduce migraine frequency in people who have migraines on 15 or more days per month. Either or both treatments may help prevent migraines.
This study tests how well Botox works for chronic migraine patients, depending on how long they've had the condition. If you have chronic migraines, haven't had Botox recently, and meet a few other conditions, you may be able to join.
This study tests a new treatment (anti-CGRP antibodies) to prevent migraine attacks from becoming chronic. It looks at whether we can predict who will respond best, aiming to find better long-term control for people with frequent or chronic migraine.
This study tests new ways to monitor how well preventive migraine treatments are working. It is for people with chronic migraine who may be starting or already using preventive medications.
This study compares two treatments for chronic migraine: injecting Botox (a nerve relaxant) versus a procedure called pulsed radiofrequency that uses energy to calm nerves in the head. It aims to find which one better reduces headache days.
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Hear when a new Migraine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.