Lower-dose duloxetine plus alpha-lipoic acid for diabetic nerve pain
Treatments studied
This study compares a lower dose of duloxetine (a pain medication) combined with alpha-lipoic acid (an antioxidant) to a standard dose of duloxetine alone, to see if the combination improves nerve pain from diabetes while possibly reducing side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have diabetes
- You have nerve pain from diabetes for at least 3 months
- Your pain is moderate to severe (score 4+ on 0-10 scale)
- You have not taken certain antidepressants, anti-seizure drugs, sedatives, or opioids in the past 4 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a combination of alpha lipoic acid (a natural antioxidant) and vitamin B supplements can help relieve nerve pain, numbness, or tingling caused by diabetes. It is for people with type 2 diabetes who have diabetic nerve damage.
This study tests whether a gentle electrical acupuncture treatment can reduce pain and numbness caused by diabetes-related nerve damage. Participants will receive treatment twice a week for 8 weeks to see if it improves symptoms and nerve function.
This trial tests if adding DLBS1033 to standard treatment can help people with diabetic neuropathy, a nerve condition causing pain or numbness from diabetes. It aims to see if it improves nerve symptoms and quality of life.
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
This study compares different treatment options for people with diabetes who have nerve pain, often called neuropathy. The goal is to find the most effective way to reduce pain and improve daily life.
This study tests whether piracetam can help relieve nerve pain caused by diabetes (peripheral neuropathy). It's for people with type 2 diabetes who use insulin and have high blood sugar levels.
Hear when a new Painful Diabetic Peripheral Neuropathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.