Lidocaine gel vs. duloxetine for diabetic nerve pain
Treatments studied
Part of Brain & nervous system, Hormones & metabolism, Pain clinical trials.
This study compares a numbing gel you put on your skin (lidocaine gel) with a daily oral medication (duloxetine) to see which works better for reducing pain from diabetic nerve damage. It aims to find a safer or more effective way to ease your pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 70 years old.
- You have had type 2 diabetes for at least one year.
- You have nerve pain in your feet or hands due to diabetes (diagnosed by your doctor).
- You are not currently taking other nerve pain medications (like gabapentin, pregabalin, or amitriptyline) or using capsaicin cream.
- You do not have any open sores, wounds, or skin problems on your feet where the gel would be applied.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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