Clin2
NCT07796373Possibly a fitNot yet recruiting

Nemtabrutinib for CLL or SLL after other treatments

Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This study tests a new oral medication, nemtabrutinib, in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that did not respond to or stopped responding to certain targeted therapies. The medication aims to control the disease when other options have not worked.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
32 people
Ages
18 years to 100 years
Study type
Interventional

Who can take part

  • You have been diagnosed with CLL or SLL and your disease has gotten worse or not improved after treatment.
  • You have already taken a Bruton tyrosine kinase inhibitor (such as ibrutinib, acalabrutinib, or pirtobrutinib) and a BCL2 inhibitor (such as venetoclax).
  • You are 18 years or older and can take oral medication.
  • You are generally able to care for yourself (ECOG performance status 0-2).
  • Your blood counts and organ function are within acceptable levels for the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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