Drug-coated balloon versus drug stent for large vessel heart blockages
Part of Heart & circulation clinical trials.
This study compares two treatments for a blocked large artery in the heart: a balloon coated with a drug (sirolimus) versus a drug-releasing stent (also sirolimus). Both aim to keep the artery open and improve blood flow, and the study uses a special ultrasound (IVUS) to guide the procedure for better outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with acute coronary syndrome (ACS), which includes unstable angina, NSTEMI, or STEMI
- You have a blockage in a large heart artery that hasn't been treated before (a 'de novo' lesion)
- Only one blockage needs treatment, and it is suitable for a balloon or stent procedure
- Your doctor will check that the blockage is ready for treatment using special imaging (IVUS)
- You do not have severe heart failure, recent heart procedures, or severe kidney/liver disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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