Clin2
NCT07813351Possibly a fitNot yet recruiting

Proton beam therapy for pituitary tumors

Acromegaly Due to Pituitary AdenomaCushing's DiseasePituitary Adenoma

Part of Bones, joints & muscles, Brain & nervous system, Cancer, Hormones & metabolism clinical trials.

This trial compares two types of radiation therapy for pituitary tumors that are still making too much hormone after surgery. It aims to see if proton beam therapy can control hormones better than standard radiation with fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
82 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a pituitary tumor that makes too much growth hormone or ACTH (causing acromegaly or Cushing's disease), confirmed by biopsy after surgery.
  • Your hormone levels are still high after surgery, without medication that lowers them.
  • Your doctors recommend radiation therapy as the next step.
  • You are 18 years or older and able to care for yourself (Karnofsky score 70 or higher).
  • You can travel to a proton therapy center (UCLH or The Christie) for treatment and follow-up visits.
  • You have not had radiation to the head or neck before, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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