New drug combo for leukemia that is no longer responding to venetoclax
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of three drugs—homoharringtonine, lisaftoclax, and azacitidine—for people with acute myeloid leukemia (AML) whose cancer did not respond to or has returned after prior treatment with venetoclax. The goal is to see if this new combination can help control the leukemia when current options have failed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of acute myeloid leukemia (AML).
- You are at least 18 years old.
- You have already tried a venetoclax-based treatment and it either did not work or your cancer came back during or after that treatment.
- Your liver and kidney function are within acceptable limits for this trial.
- You are expected to live at least 3 more months.
- You are willing to take oral medication and follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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