Mepolizumab plus in-office polyp removal for chronic sinusitis
Treatments studied
Part of Ear, nose & throat clinical trials.
This study tests whether combining mepolizumab (a biologic injection) with a quick in-office removal of nasal polyps improves symptoms better than usual care. It is for adults with chronic sinusitis and nasal polyps who qualify for biologic therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have chronic sinusitis with nasal polyps in both nasal passages.
- You have had nasal polyp surgery before or are unable to have surgery.
- You have signs of type 2 inflammation (like high eosinophils or IgE in blood or tissue).
- You have needed systemic steroids (like prednisone) or have significant symptoms like poor smell or quality of life.
- You are not pregnant, breastfeeding, or allergic to the study drug.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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