Clinical trials
Chronic Rhinosinusitis With Nasal Polyps clinical trials
Below are recruiting chronic rhinosinusitis with nasal polyps clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07860411Recruiting
Biomarker study for chronic sinusitis with nasal polyps
This study looks for certain markers in your blood and nasal tissue that may be linked to chronic sinusitis with nasal polyps. It may help doctors understand the condition better and could lead to more targeted treatments in the future.
SanliurfaAges 18 years+ - NCT05708300Recruiting
Testing how mepolizumab works for people with nasal polyps
This study looks at blood and other measures (biomarkers) to understand how well mepolizumab helps people with nasal polyps, with or without asthma. It aims to find response clues that could help personalize treatment in the future.
Thessaloniki, ExochiAges 18 years+ - NCT06129552Recruiting
Healthy nose cells study for sinusitis insight
This study is looking at healthy people to understand how certain cells in the nose work. It will compare them to people with sinus problems to learn what goes wrong in chronic sinusitis with nasal polyps.
LeuvenAges 18 years+ - NCT05938972Recruiting
Study of biologic medicines in severe CRSwNP patients
This study looks at how “biologic” medicines work in real-life care for people with severe chronic rhinosinusitis with nasal polyps (CRSwNP). It may help confirm which patients benefit and how treatment is used in everyday practice.
GhentAges 18–80 - NCT07814924RecruitingPhase 4
Mepolizumab plus in-office polyp removal for chronic sinusitis
This study tests whether combining mepolizumab (a biologic injection) with a quick in-office removal of nasal polyps improves symptoms better than usual care. It is for adults with chronic sinusitis and nasal polyps who qualify for biologic therapy.
BarakaldoAges 18–80 - NCT07782957RecruitingPhase 3
New shot for severe nasal polyps with ongoing sinus symptoms
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
Sherman Oaks, CaliforniaAges 18 years+ - NCT07782970RecruitingPhase 3
Treatment for chronic sinusitis with nasal polyps
This study tests a new medication (felcorekibart) to see if it reduces nasal polyps and symptoms like congestion and loss of smell. It may help people whose current treatments aren't enough.
Los Angeles, CaliforniaAges 18 years+ - NCT07714525RecruitingPhase 2
Steroid nanocapsules after nasal surgery
This trial tests whether a new form of steroid (triamcinolone) delivered in tiny capsules can improve healing after common nasal surgeries for chronic sinusitis or nasal polyps.
Minya, Menia GovernorateAges 18–60 - NCT07701967RecruitingPhase 4
Depemokimab for chronic sinusitis with nasal polyps
This trial tests a new antibody medicine (depemokimab) for Japanese adults with chronic sinusitis and nasal polyps. It aims to see if the drug alone can reduce symptoms without needing steroid nasal sprays.
EhimeAges 18 years+ - NCT05882903RecruitingPhase 2
Nasal steroid cream after sinus surgery for chronic sinus trouble
This trial studies whether placing a steroid nasal cream inside your sinus area can reduce symptoms in people with chronic rhinosinusitis (CRS) even after sinus surgery. It may help lower ongoing inflammation and symptoms for those who still feel unwell despite usual medical treatments.
Sydney, New South WalesAges 18–80 - NCT06683261Recruiting
Real-world study of biologics for nasal polyps
This study follows people with chronic rhinosinusitis and nasal polyps who are starting a biologic medication (omalizumab, mepolizumab, or dupilumab) to see how well it works in real life.
AalstAges 18 years+ - NCT07633158Recruiting
Real-world study of tezepelumab for chronic nasal polyps
This study follows patients with chronic rhinosinusitis with nasal polyps (CRSwNP)—a condition causing blocked sinuses and nasal growths—who are starting a new biologic medication called tezepelumab. Researchers will track how symptoms and quality of life improve over time in everyday medical practice.
BochumAges 18–130 - NCT07520162RecruitingPhase 3
Tezepelumab for Nasal Polyps in Chinese Adults
This study tests whether tezepelumab, a new injectable medicine, can help reduce nasal polyps and improve symptoms like nasal congestion, loss of smell, and sleep problems. You would receive the study drug while continuing your current nasal steroid spray, and your doctors would track how your symptoms change.
BeijingAges 18 years+ - NCT07498374Recruiting
Drug-eluting stent for eosinophilic sinusitis with nasal polyps
This trial tests a fully dissolvable stent that releases medication inside the sinuses after surgery. It is for patients with a specific type of sinusitis (eosinophilic) and nasal polyps who either need surgery or have had surgery and show early signs of inflammation returning.
Xi'an, ShaanxiAges 18–65 - NCT07436949RecruitingPhase 1/Phase 2
Study of BBT002 for chronic sinusitis with nasal polyps and asthma
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07399665Recruiting
Tezepelumab for chronic sinusitis with nasal polyps in Russia
This study tracks how well tezepelumab works for people with chronic sinusitis and nasal polyps in real-world settings. It aims to see if this medication reduces symptoms and the need for surgery.
Kazan'Ages 18 years+ - NCT07290140Recruiting
Balloon treatment for chronic sinusitis
This trial tests a balloon coated with a medicine (paclitaxel) to treat chronic sinusitis. It may help reduce inflammation and improve sinus drainage in adults with long-lasting sinus problems.
Birmingham, AlabamaAges 18 years+ - NCT07286201Enrolling by invitation
Nasal packing with steroid to improve sinus surgery results
This study tests a special nose dressing that slowly releases a steroid to reduce inflammation and improve healing after sinus surgery for chronic sinusitis with or without nasal polyps.
Colorado Springs, ColoradoAges 18 years+ - NCT07259538RecruitingPhase 1
Safety study of VVN432 nasal spray
This trial tests a nasal spray called VVN432 in healthy volunteers and people with chronic sinusitis. It checks if the spray is safe and how the body processes it.
BeijingAges 18–55 - NCT07268313RecruitingPhase 4
Remission Check for Nasal Polyp Patients on Biologics
This study looks at patients with nasal polyps and chronic sinusitis who have been stable on a biologic medicine (Dupilumab or Mepolizumab) for at least 3 months. It checks if they stay in remission (symptoms well controlled, no need for extra treatments) for a full year.
Copenhagen, Region HAges 18 years+ - NCT07187583RecruitingPhase 4
Reducing biologic doses for chronic sinusitis with polyps
This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.
AalborgAges 18 years+ - NCT07184684RecruitingPhase 2/Phase 3
Nasal bacteria transplant for chronic sinusitis
This trial tests if transplanting healthy nasal bacteria from a donor can help people with chronic sinusitis. It aims to restore a healthy microbiome in the nose to reduce symptoms like congestion and discharge.
HelsingborgAges 18 years+ - NCT07174115RecruitingPhase 2
Testing a new tablet for chronic sinusitis without nasal polyps
This trial tests an experimental tablet (HTMC0658) for people with chronic sinusitis that hasn't improved with standard nasal spray. You may join if your symptoms are moderate to severe and you've been using a stable dose of mometasone spray for at least 4 weeks.
Luoyang, HenanAges 18–75 - NCT05009758Recruiting
Asthma and nasal polyps study to match immune patterns
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
ViennaAges 18–99
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Common questions
- Are there clinical trials for chronic rhinosinusitis with nasal polyps?
- Yes. Clin2 currently lists 49 recruiting chronic rhinosinusitis with nasal polyps studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic rhinosinusitis with nasal polyps trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic rhinosinusitis with nasal polyps trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.