Trastuzumab and a new drug for advanced stomach cancer
Part of Cancer, Digestive system clinical trials.
This study tests a combination of an existing targeted drug (trastuzumab) and a new experimental drug (retlirafusp alfa) for advanced stomach cancer that has a specific marker (HER2) and did not respond to initial treatment. The goal is to see if this combination can help control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have stomach cancer or cancer where the stomach meets the esophagus that cannot be removed by surgery, has come back, or has spread.
- Your cancer tests positive for a protein called HER2 (either 3+ or 2+ on a standard test).
- Your cancer got worse after standard first-line treatment (like chemo or chemo and radiation).
- You have at least one tumor that can be measured on a scan.
- Your heart, lungs, blood, and other organs are working well enough to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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