Clin2
NCT07819864Possibly a fitNot yet recruiting

Diaphragm hibernation in ICU patients on breathing machines

Diaphragm DysfunctionWeaning Invasive Mechanical VentilationRespiratory Failure, ICU

Part of Lungs & breathing clinical trials.

This study looks at how the diaphragm—the main muscle you use to breathe—might 'hibernate' or weaken when you're on a breathing machine in the ICU. The goal is to understand why this happens and to find ways to prevent muscle weakness, which could help you recover faster.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
112 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must be 18 years or older.
  • You must be on a breathing machine (ventilator) in the intensive care unit (ICU).
  • Your doctors expect you to stay on the breathing machine for at least 72 hours (3 days) from the start of the study.
  • The first checkup can happen within 36 hours after you start using the breathing machine.
  • You must not have a pre-existing nerve or muscle disease that already affects your diaphragm (the main breathing muscle). Examples include muscular dystrophy or myasthenia gravis.
  • You must not have had home ventilation before, and must not have a known phrenic nerve (the nerve that controls the diaphragm) injury.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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