Compare diaphragm surgery versus breathing machine support
Part of Brain & nervous system, Lungs & breathing clinical trials.
This trial is studying whether surgery, instead of using a breathing machine, works better for people with one-sided diaphragm paralysis. It aims to improve breathing comfort and function in the right patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older.
- Have one-sided (unilateral) diaphragm paralysis from an isolated phrenic nerve injury.
- Your diagnosis should be at least 1 year old before starting treatment.
- Be able to give written consent (sign a study consent form).
- Have normal daytime carbon dioxide levels (not too high).
- Not have diaphragm paralysis affecting both sides.
- Not have another whole-body nerve/muscle disease causing diaphragm weakness (like ALS).
- No prior radiation to the chest and you must be eligible for diaphragm surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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