Optimizing antibiotic dosing for lung infections in the ICU
Part of Infections, Lungs & breathing clinical trials.
This study tests whether giving antibiotics in a personalized way, based on how your body processes them, works better than the standard dose for treating lung infections in the ICU. If you qualify, you'll be randomly assigned to get either the usual dose or a dose adjusted to your blood levels, with the goal of improving your recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are in the ICU and on a breathing machine (ventilator).
- You have a lung infection or signs of one, like fever, increased phlegm, or chest X-ray changes.
- You have started one of the study antibiotics (piperacillin/tazobactam or meropenem) and are expected to continue for more than 3 days.
- You don't have a known allergy to these antibiotics.
- You haven't already been on the study antibiotic for more than 48 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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