A new daily pill for lowering cholesterol in adults at high risk
Part of Hormones & metabolism clinical trials.
This study tests a new daily pill called enlicitide that lowers bad cholesterol in adults at high risk for heart problems. If you have high cholesterol despite being on a statin, this trial could help you manage your cholesterol and reduce your risk of heart attacks or strokes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had a major heart or blood vessel event (like a heart attack or stroke) OR have diabetes, a family history of very high cholesterol, or certain other heart or circulation conditions.
- Your LDL (bad) cholesterol must be at least 55 or 70 mg/dL, depending on your medical history (your doctor can check this).
- You need to be on a standard or higher dose statin, or be taking a lower dose because you couldn't tolerate a stronger one, or have documented trouble tolerating statins.
- If you are on other cholesterol-lowering medicines, your dose must be stable with no planned changes.
- You must not have had recent heart problems (like a heart attack or stroke within the last 3 months) and must not be taking certain other cholesterol medicines like PCSK9 inhibitors.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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