Tranexamic acid to reduce wound healing problems after ankle replacement
Part of Infections clinical trials.
This trial tests whether giving tranexamic acid during ankle replacement surgery helps reduce wound complications. Tranexamic acid is a medicine that helps blood clot and may reduce bleeding and swelling after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having ankle replacement surgery (either first-time or a repeat procedure).
- You can give informed consent and are willing to follow the postoperative plan and attend all follow-up visits.
- You are not pregnant or breastfeeding.
- Your diabetes, if you have it, is well-controlled (HbA1c 8 or lower).
- You are not allergic to tranexamic acid and do not have a history of blood clots, heart stents, stroke in the last 6 months, liver or kidney problems, or take certain interacting medications.
- You are not currently on blood-thinning medications, and you are not using a lateral-based ankle replacement system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a medicine called tranexamic acid (TXA) can reduce pain, improve movement, and lessen bleeding after hip or knee replacement surgery. It is for adults having their first joint replacement at St. Mary's Hospital.
This study tests whether putting tranexamic acid (a medicine that helps blood clot) directly into the bone during knee replacement surgery can reduce blood loss. It may help people recover with less need for blood transfusions.
This study tests whether giving tranexamic acid during knee surgery reduces bleeding and improves recovery. It is for people having a specific knee realignment procedure called a high tibial osteotomy.
This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.
This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.
This study tests whether a medicine called tranexamic acid (TXA), given as a shot into the hip joint or as a soak on the skin, can reduce bleeding during hip replacement surgery. It is for people over 60 who broke their hip from a simple fall and need a cementless hip replacement.
Hear when a new Ankle Arthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.